Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.62 |
| ▸ | PPARG | P37231 | 15/20 | 0.57 |
| ▸ | PPARD | Q03181 | 3/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324713 | 0.85 | PPARA (0.61) | PPARAPPARGPPARD | |
| SCHEMBL3845579 | 0.80 | PPARG (0.56) | PPARAPPARGPPARDPOLB | |
| SCHEMBL14345585 | 0.80 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL14345084 | 0.78 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL14345202 | 0.78 | USP2 (0.56) | PPARAPPARG | |
| SCHEMBL11566625 | 0.77 | PPARG (0.70) | PPARAPPARGPPARD | |
| SCHEMBL3845467 | 0.77 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL3848024 | 0.77 | ADRB3 (0.73) | PPARAPPARGPPARD | |
| SCHEMBL27674993 | 0.77 | PPARG (0.68) | PPARAPPARGPPARD | |
| SCHEMBL10183475 | 0.77 | CYP3A4 (0.60) | GABRA1GABRG2GABRB3GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141423-A1 | PPAR ENHANCING DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF | NEGMA-LERADS (FR) | 2007-12-13 | — | — | WO | disclosed |