Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327148 | 1.00 | MEN1 (0.52) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5328915 | 0.84 | KMT2A (0.72) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5328923 | 0.84 | KMT2A (0.72) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL14542415 | 0.83 | KMT2A (0.71) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5338974 | 0.81 | GAA (0.50) | MEN1KMT2AALDH1A1TP53GAA | |
| SCHEMBL14542394 | 0.80 | KMT2A (0.66) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5330488 | 0.77 | KMT2A (0.62) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5331047 | 0.77 | KMT2A (0.62) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5336137 | 0.77 | KMT2A (0.62) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5336129 | 0.77 | KMT2A (0.62) | MEN1KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | claimed |
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |