Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330488 | 1.00 | KMT2A (0.62) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL5328923 | 0.93 | KMT2A (0.72) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL5328915 | 0.93 | KMT2A (0.72) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL14542415 | 0.92 | KMT2A (0.71) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL5336137 | 0.90 | KMT2A (0.62) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL5336129 | 0.90 | KMT2A (0.62) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL14542394 | 0.88 | KMT2A (0.66) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL14542264 | 0.87 | HPGD (0.65) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL5338355 | 0.80 | TSHR (0.59) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL14542395 | 0.78 | KMT2A (0.70) | KMT2AMEN1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | claimed |
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |