Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324516 | 0.92 | DRD2 (0.57) | DRD2ADRA1AMCHR1 | |
| SCHEMBL5320287 | 0.88 | DRD2 (0.53) | DRD2ADRA1A | |
| SCHEMBL5321793 | 0.87 | DRD2 (0.56) | DRD2ADRA1AMCHR1 | |
| SCHEMBL5323020 | 0.86 | DRD2 (0.54) | DRD2ADRA1A | |
| SCHEMBL5320472 | 0.86 | DRD2 (0.51) | DRD2ADRA1A | |
| SCHEMBL5321991 | 0.85 | DRD2 (0.56) | DRD2ADRA1A | |
| SCHEMBL5327258 | 0.85 | DRD2 (0.46) | DRD2ADRA1A | |
| SCHEMBL5390458 | 0.84 | DRD2 (0.64) | DRD2ADRA1A | |
| SCHEMBL5324721 | 0.84 | DRD2 (0.56) | DRD2ADRA1A | |
| SCHEMBL4616971 | 0.84 | DRD2 (0.67) | DRD2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | claimed |