Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297246 | 0.78 | HSP90AA1 (0.50) | LMNAACHEHSP90AA1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL713375 | 0.77 | HSP90AA1 (0.53) | LMNAACHEHSP90AA1KMT2AALDH1A1 | |
| SCHEMBL5562270 | 0.75 | KMT2A (0.50) | ACHEHSP90AA1KMT2AALDH1A1POLB | |
| SCHEMBL7048071 | 0.74 | HSP90AA1 (0.50) | LMNAACHEHSP90AA1KMT2AALDH1A1 | |
| SCHEMBL8120184 | 0.74 | KMT2A (0.50) | LMNAACHEHSP90AA1KMT2AALDH1A1 | |
| SCHEMBL16674109 | 0.74 | HSP90AA1 (0.59) | LMNAACHEHSP90AA1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL614210 | 0.73 | KMT2A (0.48) | LMNAACHEHSP90AA1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL5847774 | 0.72 | HSP90AA1 (0.53) | LMNAACHEHSP90AA1KMT2AALDH1A1 | |
| SCHEMBL7045863 | 0.71 | HSP90AA1 (0.47) | LMNAACHEHSP90AA1KMT2AALDH1A1 | |
| Benzene SCHEMBL27350316 | 0.70 | CRBN (0.38) | LMNAKMT2AALDH1A1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132179-A2 | THERAPEUTICS COMPRISING PYRIDINIUM DERIVATIVES | UNIVERSITY OF BATH (GB) | 2007-11-22 | — | — | WO | disclosed |