⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3673710 | 0.91 | TSHR (0.46) | — | |
| SCHEMBL20530377 | 0.89 | TSHR (0.43) | — | |
| SCHEMBL30879536 | 0.89 | TSHR (0.43) | — | |
| SCHEMBL2182376 | 0.89 | TSHR (0.43) | — | |
| SCHEMBL464424 | 0.88 | — | — | |
| SCHEMBL573231 | 0.88 | — | — | |
| Water SCHEMBL573385 | 0.88 | TSHR (0.37) | — | |
| Water SCHEMBL573386 | 0.88 | — | — | |
| SCHEMBL19175930 | 0.87 | TSHR (0.32) | — | |
| SCHEMBL20758295 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346555-A1 | METHOD FOR CO-PRODUCING VALPROAMIDE AND SODIUM VALPROATE | HUNAN XIANGZHONG PHARMACEUTICAL CO LTD (CN) | 2025-11-13 | — | — | US | claimed |
| CN-119930467-A | Preparation method of 2-cyano-2-propyl valerate and valproic acid | 湖南省湘中制药有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-118388335-A | Method for controlling impurities in valproic acid | 湖南省湘中制药有限公司 | 2024-07-26 | — | — | CN | claimed |
| WO-2023221851-A1 | METHOD FOR CO-PRODUCING VALPROAMIDE AND SODIUM VALPROATE | 湖南省湘中制药有限公司 | 2023-11-23 | — | — | WO | claimed |
| CN-116143586-A | Preparation method of 2-ethyl-2-methyl valeric acid | 上海青平药业有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-114763319-B | Method for co-producing valproamide and sodium valproate | 湖南大学 | 2023-03-31 | — | — | CN | claimed |
| CN-114763319-A | Method for co-producing valproamide and sodium valproate | 湖南大学 | 2022-07-19 | — | — | CN | claimed |
| US-8895478-B2 | Degradable polymer compositions and uses thereof | ISP INVESTMENTS INC. (US) | 2014-11-25 | — | — | US | claimed |
| US-20120157352-A1 | DEGRADABLE POLYMER COMPOSITIONS AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2012-06-21 | — | — | US | claimed |
| EP-2414456-A1 | DEGRADABLE POLYMER COMPOSITIONS AND USES THEREOF | Isp Investments Inc. (US) | 2012-02-08 | — | — | EP | claimed |
| US-5075486-A | Heating N-/1-propyl-n-butyl/formamide in absence of oxygen wit h alkali metal/silica gel catalyst | SANOFI (FR) | 1991-12-24 | — | — | US | claimed |
| EP-0308325-B1 | PROCESS FOR THE PREPARATION OF DI-N-PROPYL ACETONITRILE | SANOFI (FR) | 1991-12-11 | — | — | EP | claimed |
| EP-0087712-B1 | METHOD FOR THE PREPARATION OF 3-CYANO-2-ALKYL ALKANALS AND USE OF 3-CYANO-2-ETHYL HEXANAL IN THE PREPARATION OF 2-PROPYLPENTANOIC ACID | BASF Aktiengesellschaft (DE) | 1986-05-07 | — | — | EP | claimed |
| EP-0030528-B1 | PROCESS FOR THE INTRODUCTION OF ALKYL, ARALKYL OR CYCLOALKYL GROUPS ONTO A FUNCTIONAL GROUP-SUBSTITUTED CARBON CHAIN | SANOFI S.A. (FR) | 1983-06-22 | — | — | EP | claimed |
| US-RE31260-E | Process for the preparation of an acetonitrile derivative | LABAZ (FR) | 1983-05-31 | — | — | US | claimed |
| US-4377533-A | PROPYLATION OF NITRILES | SANOFI (FR) | 1983-03-22 | — | — | US | claimed |
| EP-0030528-A1 | Process for the introduction of alkyl, aralkyl or cycloalkyl groups onto a functional group-substituted carbon chain | SANOFI S.A. (FR) | 1981-06-17 | — | — | EP | claimed |
| US-4155929-A | Process for the preparation of an acetonitrile derivative | LABAZ (FR) | 1979-05-22 | — | — | US | claimed |
| US-4127607-A | DIPROPYLACETAMIDE BY ACID HYDROLYSIS OF DIPROPYLACETONITRILE WITH SULFURIC ACID | LABAZ (FR) | 1978-11-28 | — | — | US | claimed |
| US-4127604-A | Process for the preparation of acetic acid derivatives | LABAZ (FR) | 1978-11-28 | — | — | US | claimed |