Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327705 | 1.00 | SLC6A4 (0.46) | SLC6A4HTR6CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5329150 | 1.00 | SLC6A4 (0.46) | SLC6A4HTR6CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL23105313 | 0.76 | NPC1 (0.43) | SLC6A4CYP2D6HTR2CHTR2BSSTR4 | |
| SCHEMBL23105314 | 0.76 | NPC1 (0.43) | SLC6A4CYP2D6HTR2CHTR2BSSTR4 | |
| SCHEMBL29569182 | 0.76 | NPC1 (0.43) | SLC6A4CYP2D6HTR2CHTR2BSSTR4 | |
| SCHEMBL15372401 | 0.76 | CYP1A2 (0.44) | SLC6A4CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5322220 | 0.75 | TAAR1 (0.47) | SLC6A4HTR6CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5322223 | 0.75 | TAAR1 (0.47) | SLC6A4HTR6CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5322226 | 0.75 | TAAR1 (0.47) | SLC6A4HTR6CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4500135 | 0.75 | SLC6A4 (0.52) | SLC6A4HTR6CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135529-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |