Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779313 | 0.88 | TACR1 (0.54) | TACR1 | |
| SCHEMBL4461016 | 0.83 | TACR1 (1.00) | TACR1 | |
| SCHEMBL13954730 | 0.83 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8540356 | 0.81 | TACR1 (0.65) | TACR1 | |
| SCHEMBL9220669 | 0.81 | TACR1 (0.65) | TACR1 | |
| SCHEMBL13934970 | 0.75 | TACR1 (1.00) | TACR1 | |
| SCHEMBL7183608 | 0.72 | TACR1 (0.59) | TACR1 | |
| SCHEMBL7181839 | 0.72 | TACR1 (0.81) | TACR1 | |
| SCHEMBL4469839 | 0.71 | TACR1 (0.81) | TACR1 | |
| SCHEMBL9165199 | 0.71 | TACR1 (0.79) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007136570-A2 | 5,6-FUSED PYRROLIDINE COMPOUNDS USEFUL AS TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2007-11-29 | — | — | WO | disclosed |