Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 0.75 |
| ▸ | HTR2A | P28223 | 16/20 | 0.75 |
| ▸ | HTR1A | P08908 | 8/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.75 |
| ▸ | HTR2C | P28335 | 3/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.75 |
| ▸ | HRH1 | P35367 | 3/20 | 0.75 |
| ▸ | ACHE | P22303 | 3/20 | 0.75 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.75 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.75 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.75 |
| ▸ | DRD1 | P21728 | 2/20 | 0.75 |
| ▸ | DRD4 | P21917 | 2/20 | 0.75 |
| ▸ | DRD5 | P21918 | 2/20 | 0.75 |
| ▸ | HTR1D | P28221 | 2/20 | 0.75 |
| ▸ | HTR1B | P28222 | 2/20 | 0.75 |
| ▸ | HTR7 | P34969 | 2/20 | 0.75 |
| ▸ | DRD3 | P35462 | 2/20 | 0.75 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.75 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322886 | 0.90 | DRD2 (0.64) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL1119172 | 0.88 | DRD2 (0.75) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| Risperidone SCHEMBL29392548 | 0.86 | DRD2 (1.00) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| Risperidone SCHEMBL16965766 | 0.86 | DRD2 (1.00) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| Risperidone SCHEMBL5070793 | 0.86 | DRD2 (1.00) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| Risperidone SCHEMBL27911 | 0.86 | DRD2 (1.00) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| Risperidone SCHEMBL5774262 | 0.85 | DRD2 (0.98) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| Risperidone SCHEMBL28382198 | 0.85 | DRD2 (0.98) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL1842717 | 0.85 | HTR2A (0.76) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| Risperidone SCHEMBL20578557 | 0.85 | DRD2 (0.98) | DRD2HTR2AHTR1AKCNH2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138462-A2 | AQUEOUS ORAL FORMULATIONS OF RISPERIDONE | WOCKHARDT LTD (IN) | 2007-12-06 | — | — | WO | disclosed |
| EP-1490090-A4 | ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS | NEW RIVER PHARMACEUTICALS INC (US) | 2006-09-20 | — | — | EP | disclosed |
| EP-1534288-A1 | STABLE AQUEOUS SOLUTIONS OF RISPERIDONE AND METHODS FOR THEIR PREPARATION | RANBAXY LABORATORIES, LTD. (IN) | 2005-06-01 | — | — | EP | disclosed |
| EP-1490090-A2 | ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS | New River Pharmaceuticals Inc. (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2004017975-A1 | STABLE AQUEOUS SOLUTIONS OF RISPERIDONE AND METHODS FOR THEIR PREPARATION | RANBAXY LABORATORIES LIMITED (IN) | 2004-03-04 | — | — | WO | disclosed |
| WO-2003079972-A2 | ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS | NEW RIVER PARMACEUTICALS INC. (US) | 2003-10-02 | — | — | WO | disclosed |
| EP-1165090-A2 | A METHOD OF TREATING BULIMIA NERVOSA AND RELATED EATING DISORDERS BY ADMINISTRATION OF ATYPICAL ANTIPSYCHOTIC MEDICATIONS | Children's Hospital Research Foundation (US) | 2002-01-02 | — | — | EP | disclosed |
| EP-1140029-A1 | PREPARATION OF MICROPARTICLES HAVING A SELECTED RELEASE PROFILE | Alkermes Controlled Therapeutics Inc. II (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000054764-A2 | A METHOD OF TREATING BULIMIA NERVOSA AND RELATED EATING DISORDERS BY ADMINISTRATION OF ATYPICAL ANTIPSYCHOTIC MEDICATIONS | CHILDREN'S HOSPITAL RESEARCH FOUNDATION (US) | 2000-09-21 | — | — | WO | disclosed |
| WO-2000040221-A1 | PREPARATION OF MICROPARTICLES HAVING A SELECTED RELEASE PROFILE | ALKERMES CONTROLLED THERAPEUTICS INC. II (US) | 2000-07-13 | — | — | WO | disclosed |
| EP-0196132-A2 | 1,2-Benzisoxazol-3-yl and 1,2-benzisothiazol-3-yl derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-10-01 | — | — | EP | disclosed |