Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 5/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | CTSC | P53634 | 2/20 | 0.43 |
| ▸ | YARS1 | P54577 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8866327 | 0.94 | ESR1 (0.49) | SMN1; SMN2ALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL5304216 | 0.92 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL5304987 | 0.92 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1HTTNCOA1NCOA3 | |
| Acetic Acid SCHEMBL8866661 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL8866336 | 0.87 | ESR1 (0.43) | SMN1; SMN2ALDH1A1HTTNCOA1NCOA3 | |
| Maleic Acid SCHEMBL8866899 | 0.86 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1HTTNCOA1NCOA3 | |
| Fumaric Acid SCHEMBL8866914 | 0.86 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL6813188 | 0.82 | ALDH1A1 (0.71) | SMN1; SMN2ALDH1A1HTTNCOA1NCOA3 | |
| SCHEMBL16889096 | 0.82 | ALDH1A1 (0.71) | SMN1; SMN2ALDH1A1HTTNCOA1NCOA3 | |
| Hydrochloric Acid SCHEMBL6813768 | 0.81 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1HTTNCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017652-A2 | ARYLAKYLAMINES FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | claimed |
| EP-0356035-B1 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | ASTRA AB (SE) | 1996-03-13 | — | — | EP | claimed |
| WO-1991011995-A1 | ARYLALKYL-AMINES AND -AMIDES HAVING ANTICONVULSANT AND NEUROPROTECTIVE PROPERTIES | FISONS CORPORATION (US) | 1991-08-22 | — | — | WO | claimed |
| EP-0356035-A2 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | Astra Aktiebolag (SE) | 1990-02-28 | — | — | EP | claimed |
| WO-2007017652-A2 | ARYLAKYLAMINES FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | disclosed |