Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 13/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5284221 | 0.87 | PTH1R (0.53) | PTH1R | |
| SCHEMBL5344822 | 0.86 | PTH1R (0.53) | PTH1R | |
| SCHEMBL5343741 | 0.79 | PTH1R (0.80) | PTH1R | |
| SCHEMBL5355993 | 0.76 | PTH1R (0.53) | PTH1RMEN1KMT2AALDH1A1 | |
| SCHEMBL5320380 | 0.75 | PTH1R (0.57) | PTH1RMEN1KMT2AMAPTGAA | |
| SCHEMBL5322629 | 0.75 | PTH1R (0.63) | PTH1R | |
| SCHEMBL5320662 | 0.75 | PTH1R (0.54) | PTH1RMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5328105 | 0.75 | PTH1R (0.54) | PTH1RMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5343663 | 0.73 | PTH1R (0.62) | PTH1R | |
| SCHEMBL5328196 | 0.73 | PTH1R (0.52) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |