Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 17/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319870 | 0.87 | PTH1R (0.60) | PTH1RMEN1KMT2AALDH1A1 | |
| SCHEMBL5362907 | 0.87 | PTH1R (0.55) | PTH1R | |
| SCHEMBL5358610 | 0.80 | PTH1R (0.61) | PTH1RMEN1KMT2AALDH1A1 | |
| SCHEMBL5352610 | 0.78 | PTH1R (0.54) | PTH1R | |
| SCHEMBL5322629 | 0.78 | PTH1R (0.63) | PTH1R | |
| SCHEMBL5328340 | 0.76 | PTH1R (0.50) | PTH1RMEN1KMT2AALDH1A1 | |
| SCHEMBL5343663 | 0.76 | PTH1R (0.62) | PTH1R | |
| SCHEMBL5320662 | 0.73 | PTH1R (0.54) | PTH1RMEN1KMT2AALDH1A1 | |
| SCHEMBL5328105 | 0.73 | PTH1R (0.54) | PTH1RMEN1KMT2AALDH1A1 | |
| SCHEMBL5347210 | 0.73 | PTH1R (0.65) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135350-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |