Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.42 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322728 | 0.81 | GRM2 (0.51) | GRM2DRD4DRD2DRD3LMNA | |
| SCHEMBL5322682 | 0.74 | GRM2 (0.56) | GRM2DRD4DRD2DRD3LMNA | |
| SCHEMBL5326693 | 0.71 | GRM2 (0.51) | SMN1; SMN2GRM2DRD4DRD2DRD3 | |
| SCHEMBL5328000 | 0.71 | GRM2 (0.55) | SMN1; SMN2GRM2DRD4DRD2DRD3 | |
| SCHEMBL5327996 | 0.71 | GRM2 (0.55) | SMN1; SMN2GRM2DRD4DRD2DRD3 | |
| SCHEMBL5321874 | 0.71 | GRM2 (0.55) | SMN1; SMN2GRM2DRD4DRD2DRD3 | |
| SCHEMBL5324285 | 0.71 | GRM2 (0.55) | SMN1; SMN2GRM2DRD4DRD2DRD3 | |
| SCHEMBL5325773 | 0.71 | GRM2 (0.55) | SMN1; SMN2GRM2DRD4DRD2DRD3 | |
| SCHEMBL5328515 | 0.70 | GRM2 (0.59) | GRM2DRD4DRD2DRD3 | |
| SCHEMBL5321848 | 0.70 | GRM2 (0.49) | GRM2DRD4DRD2DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |