Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26460992 | 0.96 | EPHX1 (0.52) | EPHX1MAPK1BTKHRH3CHRM2 | |
| SCHEMBL1296115 | 0.85 | EPHX1 (0.41) | EPHX1MAPK1BTKHRH3CHRM2 | |
| SCHEMBL1297808 | 0.83 | BTK (0.38) | EPHX1MAPK1BTKHRH3CHRM2 | |
| SCHEMBL15023147 | 0.82 | BTK (0.47) | MAPK1BTKMEN1KMT2A | |
| SCHEMBL8140944 | 0.82 | CHRM2 (0.43) | EPHX1BTKCHRM2CHRM3GAA | |
| SCHEMBL23004339 | 0.82 | BTK (0.47) | MAPK1BTKMEN1KMT2A | |
| SCHEMBL18309090 | 0.82 | BTK (0.37) | EPHX1MAPK1BTKHRH3CHRM2 | |
| SCHEMBL18590666 | 0.82 | BTK (0.47) | MAPK1BTKMEN1KMT2A | |
| SCHEMBL8181924 | 0.82 | CHRM2 (0.43) | EPHX1BTKCHRM2CHRM3GAA | |
| SCHEMBL2502211 | 0.80 | BTK (0.39) | EPHX1MAPK1BTKHRH3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144379-A1 | BICYCLIC COMPOUNDS USEFUL AS CATHEPSIN S INBHIBITORS | MEDIVIR AB (SE) | 2007-12-21 | — | — | WO | disclosed |