Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181924 | 1.00 | CHRM2 (0.43) | CHRM2CHRM4CHRM3SLC6A2BTK | |
| SCHEMBL1296390 | 0.96 | SLC6A2 (0.46) | CHRM2CHRM4CHRM3SLC6A2BTK | |
| SCHEMBL1296115 | 0.87 | EPHX1 (0.41) | CHRM2CHRM3SLC6A2BTKDGAT1 | |
| SCHEMBL6159678 | 0.85 | DGAT1 (0.41) | CHRM2CHRM4CHRM3BTKDGAT1 | |
| SCHEMBL6159675 | 0.85 | DGAT1 (0.41) | CHRM2CHRM4CHRM3BTKDGAT1 | |
| SCHEMBL6160832 | 0.85 | DGAT1 (0.41) | CHRM2CHRM4CHRM3BTKDGAT1 | |
| SCHEMBL9133786 | 0.85 | CHRM2 (0.53) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL9133791 | 0.85 | CHRM2 (0.53) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL4614064 | 0.85 | CHRM2 (0.53) | CHRM2CHRM4CHRM3SLC6A2SLC6A4 | |
| SCHEMBL23004339 | 0.84 | BTK (0.47) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119772-A1 | AMIDE DERIVATIVES AS INHIBITORS OF ASPARTYL PROTEASES | MEDIVIR AB (SE) | 2008-10-09 | — | — | WO | disclosed |