Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4888087 | 0.98 | PKM (0.62) | PKMMAPTHTR2CHTR2BALDH1A1 | |
| SCHEMBL4479351 | 0.84 | APOBEC3G (0.58) | PKMHTR2CALDH1A1KDM4EGAA | |
| SCHEMBL333988 | 0.78 | PKM (1.00) | PKMMAPTKDRMCOLN3TSHR | |
| Hydrochloric Acid SCHEMBL5336085 | 0.77 | PKM (0.58) | PKMMAPTALDH1A1TSHRHTR7 | |
| SCHEMBL31142569 | 0.77 | GAA (0.57) | PKMMAPTALDH1A1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL932094 | 0.77 | PKM (0.97) | PKMMAPTKDRMCOLN3TSHR | |
| SCHEMBL568043 | 0.76 | ROCK1 (0.60) | PKMMAPTHTR2CHTR2BALDH1A1 | |
| SCHEMBL5204276 | 0.76 | PKM (0.73) | PKMMAPTALDH1A1MCOLN3TSHR | |
| SCHEMBL8278490 | 0.76 | MCOLN3 (0.59) | MAPTHTR2CHTR2BKDM4EGAA | |
| SCHEMBL2266915 | 0.76 | PKM (0.73) | PKMMAPTALDH1A1MCOLN3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008145-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |