Cyclophosphamide Anhydrous

Cyclophosphamide Anhydrous

SCHEMBL5328735

O=P1(N(CCCl)CCCl)NCCCO1.O=P1(N(CCCl)CCCl)NCCCO1.O=P1(N(CCCl)CCCl)NCCCO1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 1.00
KDM4E B2RXH2 1/20 0.96
ALOX15 P16050 1/20 0.96
MAPK1 P28482 1/20 0.96
CRYZ Q08257 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclophosphamide Anhydrous SCHEMBL28088100 1.00 NPSR1 (1.00) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL7304 1.00 NPSR1 (1.00) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL14192809 1.00 NPSR1 (1.00) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL4346 1.00 NPSR1 (1.00) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL1285823 1.00 NPSR1 (1.00) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL20542636 1.00 NPSR1 (1.00) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL4994883 0.98 NPSR1 (0.96) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL5802618 0.98 NPSR1 (0.96) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL6071 0.98 KDM4E (1.00) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL5436000 0.98 KDM4E (1.00) NPSR1KDM4EALOX15MAPK1CRYZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007149103-A2 VASCULAR TISSUE ENHANCEMENT AND SELECTIVE DESTRUCTION OF CANCEROUS CELLULAR TISSUE KAISER DANIEL E (US) 2007-12-27 WO claimed
US-5658945-A ANTICANCER AGENT; AIDS THERAPY; CONTROLLING INFECTIONS AMERICAN CYANAMID COMPANY (US) 1997-08-19 US disclosed
US-5633280-A ACCELERATED RECOVERY FROM CHEMOTHERAPY, RADIATION TREATMENT, BONE MARROW TRANSPLANTATION, INFECTIONS AMERICAN CYANAMID COMPANY (US) 1997-05-27 US disclosed
US-5616612-A THERAPY FOR CANCER, AIDS, ANEMIA, INFECTIONS AMERICAN CYANAMID COMPANY (US) 1997-04-01 US disclosed
US-5602275-A MAY BE USED TO ACCELERATE RECOVERY FROM NEUTROPENIA ACCOMPANYING RADIO- OR CHEMOTHERAPY, BONE MARROW TRANSPLANTATION OR INFECTIONS AMERICAN CYANAMID COMPANY (US) 1997-02-11 US disclosed
US-5545662-A USED TO ACCELERATE RECOVERY FROM NEUTROPENIA ACCOMPANYING RADIO OR CHEMOTHERAPY, BONE MARROW TRANSPLANTATION, OR INFECTIONS AMERICAN CYANAMID COMPANY (US) 1996-08-13 US disclosed
US-5312831-A Immunology, anticarcinogenic agents and AIDS treatment AMERICAN CYANAMID COMPANY (US) 1994-05-17 US disclosed