Cyclophosphamide Anhydrous

Cyclophosphamide Anhydrous

SCHEMBL14192809

O=[P@]1(N(CCCl)CCCl)NCCCO1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 1.00
KDM4E B2RXH2 1/20 0.96
ALOX15 P16050 1/20 0.96
MAPK1 P28482 1/20 0.96
CRYZ Q08257 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclophosphamide Anhydrous SCHEMBL28088100 1.00 NPSR1 (1.00) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL7304 1.00 NPSR1 (1.00) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL4346 1.00 NPSR1 (1.00) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL5328735 1.00 NPSR1 (1.00) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL1285823 1.00 NPSR1 (1.00) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL20542636 1.00 NPSR1 (1.00) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL4994883 0.98 NPSR1 (0.96) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL5802618 0.98 NPSR1 (0.96) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL6071 0.98 KDM4E (1.00) NPSR1KDM4EALOX15MAPK1CRYZ
Cyclophosphamide Anhydrous SCHEMBL5436000 0.98 KDM4E (1.00) NPSR1KDM4EALOX15MAPK1CRYZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4329878-A1 USE OF ONCOLYTIC ADENOVIRUS FOR THE TREATMENT OF PEDIATRIC BRAIN CANCER Dnatrix, Inc. (US) 2024-03-06 EP claimed
WO-2022232176-A1 USE OF ONCOLYTIC ADENOVIRUS FOR THE TREATMENT OF PEDIATRIC BRAIN CANCER DNATRIX, INC. (US) 2022-11-03 WO claimed
EP-4648776-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT AND/OR PREVENTION OF TYPE 1 DIABETES Pfizer Inc. (US) 2025-11-19 EP disclosed
US-12433905-B2 Stable oral composition of cyclophosphamide INTAS PHARMACEUTICALS LTD. (IN) 2025-10-07 US disclosed
CN-119909198-A Alpha-cyperus ketone bionic nano preparation and preparation method and application thereof 宁夏医科大学总医院 2025-05-02 CN disclosed
WO-2024229600-A1 SOLUBLE BIOMOLECULAR GLASS AND USE THEREOF 中国科学院过程工程研究所 2024-11-14 WO disclosed
EP-4440554-A1 A PHARMACEUTICAL FORMULATION AND A PROCESS FOR ITS PREPARATION Sava Healthcare Ltd (IN) 2024-10-09 EP disclosed
WO-2024150110-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT AND/OR PREVENTION OF TYPE 1 DIABETES PFIZER INC. (US) 2024-07-18 WO disclosed
EP-4329878-A1 USE OF ONCOLYTIC ADENOVIRUS FOR THE TREATMENT OF PEDIATRIC BRAIN CANCER Dnatrix, Inc. (US) 2024-03-06 EP disclosed
US-20230310468-A1 Parenteral pharmaceutical composition comprising cyclophosphamide and a mixture of liquids SANDOZ AG (CH) 2023-10-05 US disclosed
US-20230310468-A1 Parenteral pharmaceutical composition comprising cyclophosphamide and a mixture of liquids SANDOZ AG (CH) 2023-10-05 US disclosed
CN-116322766-A anti-CD 2 antibodies 泽拉里翁马耳他有限公司 2023-06-23 CN disclosed
WO-2023099968-A1 A PHARMACEUTICAL FORMULATION AND A PROCESS FOR ITS PREPARATION SAVA HEALTHCARE LTD (IN) 2023-06-08 WO disclosed
WO-2022232176-A1 USE OF ONCOLYTIC ADENOVIRUS FOR THE TREATMENT OF PEDIATRIC BRAIN CANCER DNATRIX, INC. (US) 2022-11-03 WO disclosed
US-20220265688-A1 STABLE ORAL COMPOSITION OF CYCLOPHOSPHAMIDE INTAS PHARMACEUTICALS LTD. (IN) 2022-08-25 US disclosed
EP-4003390-A1 METHOD FOR TREATING SOLID TUMORS Breakbio Corp. (US) 2022-06-01 EP disclosed
EP-3996685-A1 STABLE ORAL COMPOSITION OF CYCLOPHOSPHAMIDE Intas Pharmaceuticals Ltd. (IN) 2022-05-18 EP disclosed
WO-2008076257-A2 TREATING CANCER WITH ANTI-IGFLR ANTIBODY 19D12 = SCH 717454 SCHERING CORPORATION (US) 2008-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230310468-A1 Parenteral pharmaceutical composition comprising cyclophosphamide and a mixture of liquids CXCR3, CCR3, FCGRT NPSR1 4110/4885KDM4E 1668/4885ALOX15 1531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.