Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.58 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517098 | 0.78 | GSK3A (0.52) | SCN2ALMNAMAPTMEN1KMT2A | |
| SCHEMBL17172464 | 0.77 | MAPT (0.57) | HPNSCN2ALMNATSHRMAPT | |
| SCHEMBL3027634 | 0.77 | GAA (0.47) | HPNSCN2ALMNAMAPTMEN1 | |
| SCHEMBL23296154 | 0.76 | DDB1 (0.57) | HPNSCN2ALMNATSHRMAPT | |
| SCHEMBL6978711 | 0.75 | GAA (0.65) | HPNSCN2AMAPTMEN1KMT2A | |
| SCHEMBL10889569 | 0.75 | PDE4A (0.57) | HPNSCN2AMAPTMEN1KMT2A | |
| SCHEMBL28074096 | 0.75 | MAPT (0.54) | HPNSCN2ALMNATSHRMAPT | |
| SCHEMBL29624296 | 0.74 | HPN (0.49) | HPNSCN2ALMNATSHRMAPT | |
| SCHEMBL2029909 | 0.74 | HPN (1.00) | HPNSCN2ALMNATSHRMAPT | |
| SCHEMBL30532190 | 0.74 | HPN (1.00) | HPNSCN2ALMNATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141390-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIVIRAL AGENTS | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2007-12-13 | — | — | WO | claimed |
| WO-2007141390-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIVIRAL AGENTS | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2007-12-13 | — | — | WO | disclosed |