Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 1.00 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.66 |
| ▸ | MGLL | Q99685 | 8/20 | 0.62 |
| ▸ | FAAH | O00519 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30532190 | 1.00 | HPN (1.00) | HPNSCN2AMGLLFAAHLMNA | |
| SCHEMBL12127316 | 0.84 | HPN (0.72) | HPNSCN2AMGLLFAAHHSP90AA1 | |
| SCHEMBL10587599 | 0.81 | HPN (0.68) | HPNSCN2AMGLLFAAHTSHR | |
| SCHEMBL17044675 | 0.81 | HPN (0.68) | HPNSCN2AMGLLFAAHLMNA | |
| SCHEMBL10854270 | 0.81 | HPN (0.68) | HPNSCN2ALMNATSHRMAPT | |
| SCHEMBL11669113 | 0.79 | SCN2A (1.00) | HPNSCN2ALMNATSHRMAPT | |
| SCHEMBL30758587 | 0.79 | SCN2A (1.00) | HPNSCN2ALMNATSHRMAPT | |
| SCHEMBL6140131 | 0.78 | HPN (0.64) | HPNSCN2ALMNATSHRMAPT | |
| SCHEMBL94730 | 0.78 | MGLL (1.00) | HPNMGLLFAAHHSP90AA1ALDH1A1 | |
| SCHEMBL1838889 | 0.78 | MGLL (1.00) | HPNMGLLFAAHHSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110724154-A | Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof | 湖北科技学院 | 2020-01-24 | — | — | CN | claimed |
| CN-114432301-B | Covalent inhibitor derivative and application thereof in treatment of viral infection | 北京大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-116802304-A | Polynucleotides and methods for transferring resistance to asian soybean rust | 先锋国际良种公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-115826360-B | Photosensitive polyimide composition, method for producing pattern, cured product, and electronic component | 江苏艾森半导体材料股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-113136239-B | Utilization method of ethylene cracking tar and application of compound containing carbon-carbon double bond | 清华大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-114432301-A | Covalent inhibitor derivative and application thereof in treating virus infection | 北京大学 | 2022-05-06 | — | — | CN | disclosed |
| US-20220064195-A1 | SYNTHETIC I2 IMIDAZOLINE RECEPTOR LIGANDS FOR PREVENTION OR TREATMENT OF HUMAN BRAIN DISORDERS | UNIVERSITAT DE LES ILLES BALEARS (ES) | 2022-03-03 | — | — | US | disclosed |
| CN-113563152-A | Method for treating C five fraction and use of olefinic bond-containing compound | 清华大学 | 2021-10-29 | — | — | CN | disclosed |
| EP-3897838-A1 | <SUP2/>? <SUB2/>?2?SYNTHETIC IIMIDAZOLINE RECEPTOR LIGANDS FOR PREVENTION OR TREATMENT OF HUMAN BRAIN DISORDERS | Universitat de Barcelona (ES) | 2021-10-27 | — | — | EP | disclosed |
| CN-113136239-A | Utilization method of ethylene cracking tar and application of compound containing carbon-carbon double bond | 清华大学 | 2021-07-20 | — | — | CN | disclosed |
| CN-1157617-A | Heterobicyclic derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-20 | — | — | CN | disclosed |
| EP-0770079-A1 | HETEROBICYCLIC DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |
| US-5612432-A | OPTICAL FILTERS FOR DISPLAY DEVICES AND SUBSTRATES FOR LIQUID CRYSTAL DISPLAY DEVICES AND OPTICAL LENSES | TORAY INDUSTRIES, INC. (JP) | 1997-03-18 | — | — | US | disclosed |
| EP-0503097-B1 | OPTICAL SHEET MATERIAL | TORAY INDUSTRIES (JP) | 1996-03-13 | — | — | EP | disclosed |
| WO-1996001825-A1 | HETEROBICYCLIC DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-01-25 | — | — | WO | disclosed |
| EP-0503097-A1 | OPTICAL SHEET MATERIAL | TORAY INDUSTRIES, INC. (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0001997-B1 | ELECTRON BEAM-CURABLE PHOTORESIST LACQUERS | BAYER AG (DE) | 1981-02-11 | — | — | EP | disclosed |
| EP-0001997-A1 | Electron beam-curable photoresist lacquers | BAYER AG (DE) | 1979-05-30 | — | — | EP | disclosed |
| US-4111879-A | RESIN AND AN N-ARYL-MALEIMIDE | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1978-09-05 | — | — | US | disclosed |
| US-4110294-A | POLYIMIDES | CIBA-GEIGY CORPORATION (US) | 1978-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220064195-A1 | SYNTHETIC I2 IMIDAZOLINE RECEPTOR LIGANDS FOR PREVENTION OR TREATMENT OF HUMAN BRAIN DISORDERS | CHRM1, GPR3, CHRM3 | HPN 3700/4885SCN2A 1011/4885MGLL 3253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.