Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328868 | 1.00 | TSHR (0.41) | TSHRKDM4EPOLBTACR1NPC1 | |
| SCHEMBL4889465 | 0.74 | TSHR (0.50) | TSHRKDM4EPOLBTACR1MEN1 | |
| SCHEMBL6472344 | 0.74 | TSHR (0.50) | TSHRKDM4EPOLBTACR1CA1 | |
| SCHEMBL23750706 | 0.74 | TSHR (0.50) | TSHRKDM4EPOLBTACR1CA1 | |
| SCHEMBL3334314 | 0.72 | TSHR (0.48) | TSHRKDM4EPOLBTACR1NPC1 | |
| SCHEMBL3334310 | 0.72 | TSHR (0.48) | TSHRKDM4EPOLBTACR1NPC1 | |
| SCHEMBL7921427 | 0.71 | TSHR (0.47) | TSHRKDM4EPOLBTACR1NPC1 | |
| SCHEMBL1691827 | 0.70 | TSHR (0.61) | TSHRKDM4EPOLBTACR1CA1 | |
| SCHEMBL23054322 | 0.70 | KDM4E (0.47) | TSHRKDM4EPOLBTACR1CA1 | |
| SCHEMBL23054321 | 0.70 | KDM4E (0.47) | TSHRKDM4EPOLBTACR1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144503-A2 | NOVEL PROCESS FOR PREPARING NITRONES AND N-HYDROXYLAMINES COMPRISING AT LEAST ONE HYDROXYL GROUP, AND PRODUCTS THUS OBTAINED | UNIVERSITE JOSEPH FOURIER (FR) | 2007-12-21 | — | — | WO | disclosed |