Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10346737 | 0.83 | TDP1 (0.45) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18526730 | 0.82 | KDM4E (0.53) | TSHRKDM4EPOLBARALDH1A1 | |
| SCHEMBL28173813 | 0.82 | TSHR (0.47) | TSHRKDM4EPOLBARALDH1A1 | |
| SCHEMBL23750706 | 0.81 | TSHR (0.50) | TSHRKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL6472344 | 0.81 | TSHR (0.50) | TSHRKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL9521935 | 0.81 | TSHR (0.45) | TSHRKDM4EPOLBARALDH1A1 | |
| SCHEMBL3799734 | 0.81 | IDO1 (0.46) | TSHRKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL13888734 | 0.80 | KDM4E (0.46) | TSHRKDM4EPOLBARALDH1A1 | |
| SCHEMBL10359456 | 0.79 | AR (0.36) | KDM4EPOLBARALDH1A1TACR1 | |
| SCHEMBL9521927 | 0.79 | TSHR (0.47) | TSHRKDM4EPOLBARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4356894-A1 | SUSTAINABLE PRODUCT WITH MALODORS | Beiersdorf AG (DE) | 2024-04-24 | — | — | EP | claimed |
| WO-2021038586-A1 | IMPROVED PROCESS FOR THE PREPARATION OF TEZACAFTOR INTERMEDIATE | KEMINNTEK LABORATORIES (IN) | 2021-03-04 | — | — | WO | claimed |
| US-12624051-B2 | Macrocyclic compounds, compositions, and methods of using thereof | GENZYME CORPORATION (US) | 2026-05-12 | — | — | US | disclosed |
| US-20260008786-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SCHRODINGER, LLC | 2026-01-08 | — | — | US | disclosed |
| US-20260008785-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SCHRODINGER, LLC | 2026-01-08 | — | — | US | disclosed |
| EP-4583972-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | Sionna Therapeutics Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| US-20250197422-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SCHRODINGER, LLC | 2025-06-19 | — | — | US | disclosed |
| EP-4356894-A1 | SUSTAINABLE PRODUCT WITH MALODORS | Beiersdorf AG (DE) | 2024-04-24 | — | — | EP | disclosed |
| WO-2024054840-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |
| US-20230105381-A1 | COMPOSITIONS AND METHODS FOR BIOORTHOGONAL SURFACE COATING | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-04-06 | — | — | US | disclosed |
| US-20220168280-A1 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | AMGEN INC. | 2022-06-02 | — | — | US | disclosed |
| EP-0909821-B1 | Engineering enzymes having altered substrate specificity | BASF AG (DE) | 2006-05-24 | — | — | EP | disclosed |
| EP-0911153-B1 | Image forming method | KONISHIROKU PHOTO IND (JP) | 2003-12-10 | — | — | EP | disclosed |
| US-20020034776-A1 | ALTERATION OF THE SUBSTRATE SPECIFICITY OF ENZYMES | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | US | disclosed |
| US-6174646-B1 | IMAGEWISE HEATING OR EXPOSING IMAGE FORMING MATERIAL TO LASER WHEREIN IMAGE FORMING MATERIAL COMPRISES SUPPORT HAVING RADIATION SENSITIVE LAYER CONTAINING DYE, AN ACID GENERATING COMPOUND CAPABLE OF GENERATING ACID ON IRRADIATION | KONICA CORPORATION (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0911153-A1 | Image forming method | KONICA CORPORATION (JP) | 1999-04-28 | — | — | EP | disclosed |
| EP-0909821-A2 | Engineering enzymes having altered substrate specificity | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-21 | — | — | EP | disclosed |
| US-4564476-A | Aryl fatty acid leukotriene synthesis inhibitors | MCNEILAB, INC. (US) | 1986-01-14 | — | — | US | disclosed |
| US-4324921-A | CATALYTIC ISOMERIZATION OF 5,5-DIMETHYL-1,3-DIOXANS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-04-13 | — | — | US | disclosed |
| US-4247611-A | ACETAL RESIN, ACID DONER | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12624051-B2 | Macrocyclic compounds, compositions, and methods of using thereof | CFTR, ABCC3, ABCD3 | TSHR 3205/4885KDM4E 3745/4885POLB 4117/4885 |
| US-20260008786-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | CFTR, ABCC3, ABCD3 | TSHR 3205/4885KDM4E 3745/4885POLB 4117/4885 |
| US-20260008785-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | CFTR, ABCC3, ABCD3 | TSHR 3071/4885KDM4E 3829/4885POLB 4290/4885 |
| US-20220168280-A1 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | KRAS, NRAS, HRAS | TSHR 4359/4885KDM4E 4105/4885POLB 549/4885 |
| US-20230105381-A1 | COMPOSITIONS AND METHODS FOR BIOORTHOGONAL SURFACE COATING | TYR, TH, TDO2 | TSHR 1556/4885KDM4E 3627/4885POLB 570/4885 |
| US-20250197422-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | CFTR, ABCB1, PKD1 | TSHR 2935/4885KDM4E 4252/4885POLB 1375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.