Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.75 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.75 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5278741 | 1.00 | ADRB2 (0.75) | ADRB2ADRB1ADRB3CHRM3ADRA1D | |
| Acetic Acid SCHEMBL5285823 | 0.96 | ADRB2 (0.69) | ADRB2ADRB1ADRB3 | |
| SCHEMBL5430171 | 0.92 | ADRB2 (0.70) | ADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL5287662 | 0.92 | ADRB2 (0.70) | ADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL5430614 | 0.90 | ADRB2 (0.74) | ADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL5430606 | 0.90 | ADRB2 (0.74) | ADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL5280247 | 0.89 | ADRB2 (0.69) | ADRB2ADRB1ADRB3ADRA1D | |
| Acetic Acid SCHEMBL5287510 | 0.88 | ADRB2 (0.66) | ADRB2ADRB1ADRB3 | |
| Acetic Acid SCHEMBL5437977 | 0.88 | ADRB2 (0.72) | ADRB2ADRB1ADRB3ADRA1D | |
| SCHEMBL5285826 | 0.86 | ADRB2 (0.56) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497261-B1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2007-12-19 | — | — | EP | claimed |