Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863579 | 0.93 | KIF11 (0.75) | KIF11KIF23 | |
| SCHEMBL4044239 | 0.92 | KIF11 (0.68) | KIF11KIF23 | |
| SCHEMBL4066347 | 0.85 | KIF11 (0.64) | KIF11KIF23 | |
| SCHEMBL3872246 | 0.84 | KIF11 (0.74) | KIF11KIF23 | |
| SCHEMBL4069371 | 0.83 | KIF11 (0.66) | KIF11KIF23 | |
| SCHEMBL4036148 | 0.82 | KIF11 (0.64) | KIF11KIF23 | |
| SCHEMBL4039506 | 0.82 | KIF11 (0.83) | KIF11KIF23 | |
| SCHEMBL4036218 | 0.81 | KIF11 (0.87) | KIF11KIF23 | |
| SCHEMBL4058967 | 0.81 | KIF11 (0.65) | KIF11KIF23 | |
| SCHEMBL4039465 | 0.81 | KIF11 (0.79) | KIF11KIF23 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781674-A1 | ENANTIOMERS OF SELECTED FUSED PYRIMIDONES AND USES IN THE TREATMENT AND PREVENTION OF CANCER | AstraZeneca AB (SE) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006018628-A1 | ENANTIOMERS OF SELECTED FUSED PYRIMIDONES AND USES IN THE TREATMENT AND PREVENTI ON OF CANCER | ASTRAZENECA AB (SE) | 2006-02-23 | — | — | WO | disclosed |