Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 10/20 | 0.68 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245203 | 0.84 | GRM2 (0.71) | CYSLTR2CYSLTR1MEN1TSHRKMT2A | |
| SCHEMBL6243454 | 0.82 | GRM2 (0.56) | CYSLTR2CYSLTR1MEN1TSHRKMT2A | |
| SCHEMBL4797423 | 0.82 | MEN1 (0.56) | CYSLTR2CYSLTR1MEN1TSHRKMT2A | |
| SCHEMBL6248907 | 0.81 | GRM2 (0.56) | CYSLTR2CYSLTR1MEN1TSHRKMT2A | |
| Tomelukast SCHEMBL5325407 | 0.81 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MEN1TSHRKMT2A | |
| SCHEMBL10750616 | 0.81 | MEN1 (0.55) | CYSLTR2CYSLTR1MEN1TSHRKMT2A | |
| SCHEMBL9642029 | 0.80 | CYSLTR2 (0.98) | CYSLTR2CYSLTR1MEN1TSHRKMT2A | |
| SCHEMBL9643434 | 0.80 | CYSLTR2 (0.98) | CYSLTR2CYSLTR1MEN1TSHRKMT2A | |
| SCHEMBL6245616 | 0.80 | MEN1 (0.57) | CYSLTR2CYSLTR1MEN1TSHRKMT2A | |
| SCHEMBL6246396 | 0.80 | GRM2 (0.73) | CYSLTR2CYSLTR1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007127791-A2 | NEW PHARMACOLOGICAL METHOD FOR TREATMENT OF NEUROPATHIC PAIN | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2007-11-08 | — | — | WO | disclosed |