Thiophene

Thiophene

SCHEMBL5329358

c1ccc(-n2cnnn2)cc1.c1ccsc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 4/20 0.78
MAPT P10636 2/20 0.52
F2 P00734 1/20 0.52
KMT2A Q03164 3/20 0.49
RAB9A P51151 2/20 0.49
KCNJ1 P48048 2/20 0.49
SMN1; SMN2 Q16637 3/20 0.48
ALDH1A1 P00352 3/20 0.47
LMNA P02545 2/20 0.47
HTT P42858 1/20 0.47
NPSR1 Q6W5P4 1/20 0.46
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
HSD17B10 Q99714 1/20 0.44
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL342739 0.88 NOTUM (1.00) NOTUMMAPTF2KMT2ARAB9A
SCHEMBL28994295 0.86 NOTUM (0.95) NOTUMMAPTF2KMT2ARAB9A
Bromide SCHEMBL3939883 0.86 NOTUM (0.95) NOTUMMAPTF2KMT2ARAB9A
SCHEMBL3962509 0.86 NOTUM (0.95) NOTUMMAPTF2KMT2ARAB9A
Hydrochloric Acid SCHEMBL2897369 0.86 NOTUM (0.95) NOTUMMAPTF2KMT2ARAB9A
SCHEMBL7096356 0.86 NOTUM (0.95) NOTUMMAPTF2KMT2ARAB9A
SCHEMBL987888 0.81 NOTUM (0.84) NOTUMMAPTF2KMT2ARAB9A
SCHEMBL20720498 0.78 NOTUM (0.78) NOTUMMAPTF2KMT2ARAB9A
Dimethyl Sulfone SCHEMBL20720495 0.78 NOTUM (0.78) NOTUMMAPTF2KMT2ARAB9A
SCHEMBL12615985 0.77 NOTUM (0.78) NOTUMMAPTF2KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007117395-A1 A NOVEL CHEMICAL COMPOSITION TO REDUCE DEFECTS INTEL CORPORATION (US) 2007-10-18 WO claimed
US-20070228011-A1 Novel chemical composition to reduce defects INTEL CORPORATION 2007-10-04 US claimed
EP-2906640-B1 COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, METHODS FOR MAKING AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING PRC DESOTO INT INC (US) 2017-11-15 EP disclosed
EP-2756043-B1 COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING PRC DESOTO INT INC (US) 2017-04-12 EP disclosed
US-9181628-B2 Coating/sealant systems, aqueous resinous dispersions, and methods of electrocoating PRC-DESOTO INTERNATIONAL, INC. (US) 2015-11-10 US disclosed
US-9029437-B2 Coating/sealant systems, aqueous resinous dispersions, methods for making aqueous resinous dispersions, and methods of electrocoating PRC-DESOTO INTERNATIONAL, INC. (US) 2015-05-12 US disclosed
US-20130065985-A1 COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, METHODS FOR MAKING AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING PRC-DESOTO INTERNATIONAL, INC. (US) 2013-03-14 US disclosed
US-20130065057-A1 COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING PRC-DESOTO INTERNATIONAL, INC. (US) 2013-03-14 US disclosed