SCHEMBL5329366

SCHEMBL5329366

FC(F)(F)C1CC1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6416763 0.73
SCHEMBL20603736 0.73
SCHEMBL25463534 0.73
SCHEMBL20473316 0.69 APLNR (0.31)
SCHEMBL4731126 0.69
SCHEMBL24847427 0.69
SCHEMBL20603622 0.67
SCHEMBL3459547 0.67
SCHEMBL577264 0.66
SCHEMBL9294210 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213329-A Preparation method of arylpyrazole compound 中国农业科学院兰州畜牧与兽药研究所 2022-03-22 CN disclosed
WO-2007144623-A1 REFRIGERANT COMPOSITIONS INEOS FLUOR HOLDINGS LIMITED (GB) 2007-12-21 WO disclosed
WO-2007144599-A2 PRODUCTION OF FLUORINATED CYCLOPROPANES FROM THE REACTION BETWEEN CARBENES AND ALKENES INEOS FLUOR HOLDINGS LIMITED (GB) 2007-12-21 WO disclosed
US-6569404-B1 Aqueous colloidal suspension, dispersed phase is gas microbubbles of perfluoropropane, perfluorobutane, perfluoropentane, perfluorohexane or sulfur hexafluoride; fluorinated amphiphile for stabilizing microbubbles AMERSHAM HEALTH A/S (NO) 2003-05-27 US disclosed
EP-0680341-B1 PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS SONUS PHARMA INC (US) 2001-05-09 EP disclosed
EP-1038535-A2 Use of selected perfluorocarbons for the preparation of diagnostic ultrasound contrast agents SONUS PHARMACEUTICALS, INC. (US) 2000-09-27 EP disclosed
US-5876696-A Composition comprising a fluorine containing surfactant and perfluoropentane for ultrasound SONUS PHARMACEUTICALS, INC. (US) 1999-03-02 US disclosed
US-5595723-A LIQUID WITH HIGH VAPOR PRESSURE DISPERSED IN LIQUID, ULTRASOUND CONTRAST AGENTS SONUS PHARMACEUTICALS (US) 1997-01-21 US disclosed
EP-0680341-A1 PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS SONUS PHARMACEUTICALS, INC. (US) 1995-11-08 EP disclosed
WO-1994016739-A1 PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS SONUS PHARMACEUTICALS, INC. (US) 1994-08-04 WO disclosed