Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 11/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.53 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5955771 | 0.86 | GRM5 (0.49) | GRM5USP30 | |
| SCHEMBL5955780 | 0.86 | GRM5 (0.49) | GRM5USP30 | |
| SCHEMBL5333005 | 0.85 | GRM5 (0.71) | GRM5HCRTR1HCRTR2USP30MAPT | |
| SCHEMBL5333014 | 0.85 | GRM5 (0.71) | GRM5HCRTR1HCRTR2USP30MAPT | |
| SCHEMBL5628484 | 0.84 | GRM5 (0.72) | GRM5HCRTR1HCRTR2 | |
| SCHEMBL5485934 | 0.83 | GRM5 (0.55) | GRM5HCRTR1HCRTR2USP30MAPT | |
| SCHEMBL5955709 | 0.82 | GRM5 (0.57) | GRM5HCRTR1HCRTR2USP30MAPT | |
| SCHEMBL5327516 | 0.80 | HCRTR1 (0.56) | GRM5HCRTR1HCRTR2 | |
| SCHEMBL6214799 | 0.80 | GRM5 (0.43) | GRM5 | |
| SCHEMBL5306077 | 0.80 | HCRTR1 (0.53) | GRM5HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039781-A2 | NEW COMPOUNDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2007-04-12 | — | — | WO | disclosed |