Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.43 |
| ▸ | CPT1A | P50416 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5955780 | 0.92 | GRM5 (0.49) | GRM5CPT1ASCDSCD5 | |
| SCHEMBL5955771 | 0.92 | GRM5 (0.49) | GRM5CPT1ASCDSCD5 | |
| SCHEMBL5955763 | 0.81 | CHRNB2 (0.45) | GRM5 | |
| SCHEMBL5329418 | 0.80 | GRM5 (0.54) | GRM5 | |
| SCHEMBL5955736 | 0.79 | GRM5 (0.56) | GRM5CPT1A | |
| SCHEMBL5955577 | 0.79 | GRM5 (0.56) | GRM5CPT1A | |
| SCHEMBL5955860 | 0.78 | GRM5 (0.57) | GRM5CPT1A | |
| SCHEMBL5955862 | 0.78 | GRM5 (0.57) | GRM5CPT1A | |
| SCHEMBL5956161 | 0.77 | GRM5 (0.52) | GRM5CPT1A | |
| SCHEMBL5956222 | 0.77 | GRM5 (0.50) | GRM5CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581525-A2 | COMPOUNDS HAVING AN ACTIVITY AT METABOTROPIC GLUTAMATE RECEPTORS | AstraZeneca AB (SE) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004014902-A2 | COMPOUNDS HAVING AN ACTIVITY AT METABOTROPIC GLUTAMATE RECEPTORS | ASTRAZENECA AB (SE) | 2004-02-19 | — | — | WO | disclosed |