Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 3/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621542 | 0.90 | NAMPT (0.46) | NAMPTRAB9ANPC1EPHX1 | |
| SCHEMBL6224721 | 0.82 | KDM1A (0.50) | KLK7NAMPTRAB9ANPC1EPHX1 | |
| SCHEMBL23130390 | 0.81 | KDM1A (0.51) | OPRL1NAMPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL22404280 | 0.81 | KDM1A (0.53) | KLK7EPHX1 | |
| SCHEMBL21266856 | 0.81 | KDM1A (0.53) | KLK7EPHX1 | |
| SCHEMBL1565671 | 0.81 | RAB9A (0.44) | KLK7RAB9APOLBSMN1; SMN2NPC1 | |
| SCHEMBL22414312 | 0.81 | RAB9A (0.44) | KLK7RAB9APOLBSMN1; SMN2NPC1 | |
| SCHEMBL22694642 | 0.81 | KDM1A (0.53) | KLK7EPHX1 | |
| SCHEMBL24767234 | 0.81 | KDM1A (0.53) | KLK7EPHX1 | |
| SCHEMBL1240996 | 0.80 | NPC1 (0.44) | KLK7OPRL1NAMPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |