Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27658038 | 0.84 | HPGD (0.40) | HSP90AA1HPGDOPRK1HTTSLC6A3 | |
| SCHEMBL7600886 | 0.76 | HSP90AA1 (0.55) | HSP90AA1OPRK1HTTSLC6A3POLB | |
| SCHEMBL8307192 | 0.75 | SMN1; SMN2 (0.46) | HPGDPOLBMAPTTDP1ALDH1A1 | |
| SCHEMBL728962 | 0.74 | KDM4E (0.50) | HPGDHTTPOLBMAPTTDP1 | |
| SCHEMBL1354361 | 0.74 | SMN1; SMN2 (0.41) | POLBMAPTTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3667323 | 0.74 | COMT (0.44) | HTTPOLBMAPTTDP1ALDH1A1 | |
| SCHEMBL27201790 | 0.73 | PDK2 (0.49) | HPGDHTTPOLBMAPTALDH1A1 | |
| SCHEMBL3901403 | 0.73 | HPGD (0.65) | HPGDOPRK1HTTPOLBMAPT | |
| SCHEMBL28682072 | 0.72 | CA12 (0.54) | HPGDHTTPOLBMAPTTDP1 | |
| SCHEMBL8421994 | 0.72 | ALDH1A1 (0.55) | HPGDPOLBMAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007019397-A2 | 6-MEMBERED ARYL AND HETEROARYL DERIVATIVES FOR THE TREATMENT OF HEPATITIS C VIRUS | GENELABS TECHNOLOGIES, INC. (US) | 2007-02-15 | — | — | WO | disclosed |