Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 9/20 | 0.51 |
| ▸ | MMP9 | P14780 | 7/20 | 0.51 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | MMP7 | P09237 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607741 | 0.90 | TDP1 (0.50) | TDP1MMP2MMP9F2ADAMTS4 | |
| SCHEMBL14115850 | 0.90 | TDP1 (0.50) | TDP1MMP2MMP9F2ADAMTS4 | |
| SCHEMBL4597815 | 0.87 | TDP1 (0.57) | TDP1MMP2MMP9F2ADAMTS4 | |
| SCHEMBL14045373 | 0.84 | NPSR1 (0.56) | TDP1MMP2MMP9F2ADAMTS4 | |
| SCHEMBL4597319 | 0.84 | NPSR1 (0.56) | TDP1MMP2MMP9F2ADAMTS4 | |
| SCHEMBL14565793 | 0.82 | TDP1 (0.47) | TDP1MMP2MMP9F2ADAMTS4 | |
| SCHEMBL14115849 | 0.81 | TDP1 (0.50) | TDP1MMP2MMP9F2ADAMTS4 | |
| SCHEMBL4608465 | 0.81 | TDP1 (0.50) | TDP1MMP2MMP9F2ADAMTS4 | |
| SCHEMBL4597080 | 0.81 | MMP13 (0.49) | TDP1MMP2MMP9F2ADAMTS4 | |
| SCHEMBL14045372 | 0.81 | MMP13 (0.49) | TDP1MMP2MMP9F2ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005774-A9 | NOVEL DERIVATIVES OF AMINO ACIDS FOR TREATMENT OF OBESITY AND RELATED DISORDERS | BEXEL PHARMACEUTICALS INC (US) | 2007-03-08 | — | — | WO | disclosed |