Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5284607 | 0.90 | LMNA (0.55) | ALDH1A1KMT2AMEN1HTR6KDM4E | |
| SCHEMBL6038322 | 0.90 | LMNA (0.55) | ALDH1A1KMT2AMEN1HTR6KDM4E | |
| SCHEMBL6542040 | 0.87 | CACNA1B (0.46) | ALDH1A1KMT2AMEN1HTR6KDM4E | |
| SCHEMBL6542508 | 0.79 | UTS2R (0.48) | ALDH1A1HTR6CACNA1BMAPTUTS2R | |
| SCHEMBL6542002 | 0.77 | LMNA (0.63) | ALDH1A1KMT2AMEN1ALOX15MAPT | |
| SCHEMBL6542669 | 0.74 | UTS2R (0.53) | ALDH1A1KMT2AMEN1CACNA1BMAPT | |
| SCHEMBL6541270 | 0.74 | PSEN1 (0.44) | HTR6CACNA1BMAPTUTS2RLMNA | |
| SCHEMBL6541397 | 0.73 | LMNA (0.64) | ALDH1A1KMT2AMEN1ALOX15MAPT | |
| SCHEMBL213547 | 0.73 | LMNA (0.77) | ALDH1A1KMT2AMEN1HTR6KDM4E | |
| SCHEMBL6542745 | 0.72 | LMNA (0.63) | ALDH1A1KMT2AMEN1ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863804-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |