Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5287385 | 0.88 | MAPT (0.40) | TSHRMAPTPOLBALDH1A1GAA | |
| SCHEMBL5333137 | 0.85 | MAPT (0.38) | TSHRMAPTPOLBALDH1A1GAA | |
| SCHEMBL5288332 | 0.83 | TSHR (0.37) | TSHRMAPTPOLBALDH1A1GAA | |
| SCHEMBL5292198 | 0.80 | DRD2 (0.38) | TSHRMAPTPOLBALDH1A1GAA | |
| SCHEMBL5328384 | 0.80 | KMT2A (0.36) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5304804 | 0.78 | MEN1 (0.36) | TSHRMAPTPOLBALDH1A1RECQL | |
| SCHEMBL5303130 | 0.76 | KCNH2 (0.36) | ALDH1A1GAAKCNH2HTTCYP2C19 | |
| SCHEMBL5328368 | 0.76 | KCNH2 (0.36) | ALDH1A1GAAKCNH2HTTCYP2C19 | |
| SCHEMBL5324689 | 0.76 | KCNH2 (0.36) | ALDH1A1GAAKCNH2HTTCYP2C19 | |
| SCHEMBL5297697 | 0.76 | KCNH2 (0.36) | ALDH1A1GAAKCNH2HTTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779059-A | Method for coupling a first compound with a second compound | 陶氏环球技术有限责任公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-107922439-A | Process for coupling aromatic or vinyl compounds with boron-containing compounds | 陶氏环球技术有限责任公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-106687441-A | Method for coupling a first compound to a second compound | 陶氏环球技术有限责任公司 | 2017-05-17 | — | — | CN | disclosed |
| WO-2007006418-A1 | IONIC-LIQUID-CONTAINING PRODUCTS FOR DYEING AND/OR BRIGHTENING KERATIN FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-01-18 | — | — | WO | disclosed |
| WO-2006131234-A1 | COSMETIC COMPOSITIONS COMPRISING IONIC LIQUIDS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-12-14 | — | — | WO | disclosed |