Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.40 |
| ▸ | METAP1 | P53582 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331000 | 0.91 | MME (0.39) | ACEMME | |
| SCHEMBL5332031 | 0.87 | MME (0.43) | ACEMME | |
| SCHEMBL5325870 | 0.86 | MME (0.40) | ACEMMEMETAP2METAP1 | |
| SCHEMBL4949650 | 0.82 | ACE (0.46) | ACEMETAP2METAP1 | |
| SCHEMBL4955844 | 0.82 | ACE (0.46) | ACEMETAP2METAP1 | |
| SCHEMBL5332357 | 0.81 | MME (0.46) | ACEMME | |
| SCHEMBL4949670 | 0.80 | NOD1 (0.41) | ACEMMEMETAP2METAP1 | |
| SCHEMBL4956217 | 0.80 | MAPT (0.50) | ACEMETAP2METAP1 | |
| SCHEMBL14991078 | 0.80 | MAPT (0.50) | ACEMETAP2METAP1 | |
| SCHEMBL4954319 | 0.78 | NOD1 (0.41) | ACEMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147155-A1 | POLYOL ESTER COMPOUNDS | NOVUS INTERNATIONAL INC. (US) | 2007-12-21 | — | — | WO | disclosed |