Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548340 | 0.85 | HTT (0.43) | HTTLMNACA9CA12MAPT | |
| SCHEMBL11561853 | 0.79 | CA9 (0.51) | HTTLMNACA9CA12MAPT | |
| SCHEMBL7999688 | 0.77 | CA9 (0.50) | HTTLMNACA9CA12MAPT | |
| SCHEMBL11233028 | 0.75 | KDM1A (0.53) | HTTLMNACA9CA12MAPT | |
| SCHEMBL17793558 | 0.74 | HSD17B3 (0.52) | HTTLMNAALDH1A1MEN1KMT2A | |
| Formamide SCHEMBL28411125 | 0.72 | HTT (0.46) | HTTLMNACA9CA12MAPT | |
| SCHEMBL15323553 | 0.72 | NPC1 (0.52) | HTTLMNACA9CA12MAPT | |
| SCHEMBL8327473 | 0.72 | NPC1 (0.52) | HTTLMNACA9CA12MAPT | |
| SCHEMBL9400567 | 0.71 | MAPT (0.67) | LMNAMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL5653778 | 0.71 | MAPT (0.51) | LMNACA9CA12MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140989-A2 | PROCESS FOR THE MANUFACTURE OF 2-BUTYL-3- (4-METHOXYBENZOYL) -5-NITROBENZOFURANE AND USE THEREOF IN THE PRODUCTION OF OF MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2007-12-13 | — | — | WO | claimed |
| WO-2007140989-A2 | PROCESS FOR THE MANUFACTURE OF 2-BUTYL-3- (4-METHOXYBENZOYL) -5-NITROBENZOFURANE AND USE THEREOF IN THE PRODUCTION OF OF MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2007-12-13 | — | — | WO | disclosed |