Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.47 |
| ▸ | PPARD | Q03181 | 10/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | TPH1 | P17752 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14399420 | 0.93 | PPARA (0.47) | PPARAPPARDCNR1PPARGMC4R | |
| SCHEMBL5325989 | 0.93 | PPARA (0.47) | PPARAPPARDCNR1PPARGMC4R | |
| SCHEMBL5324085 | 0.92 | PPARA (0.48) | PPARAPPARDCNR1PPARGMC4R | |
| SCHEMBL14399180 | 0.85 | CNR1 (0.41) | PPARAPPARDCNR1PPARGCYP3A4 | |
| SCHEMBL5325952 | 0.84 | PPARA (0.51) | PPARAPPARDCNR1PPARGMC4R | |
| SCHEMBL5329478 | 0.84 | PPARA (0.54) | PPARAPPARDCNR1PPARG | |
| SCHEMBL14399164 | 0.83 | PPARD (0.43) | PPARAPPARDCNR1TPH1 | |
| SCHEMBL5422887 | 0.83 | TAAR1 (0.47) | PPARAPPARDCNR1PPARGTPH1 | |
| SCHEMBL5327251 | 0.83 | PPARD (0.49) | PPARAPPARDCNR1 | |
| SCHEMBL14399348 | 0.82 | CNR1 (0.44) | PPARAPPARDCNR1PPARGCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118963-A2 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118963-A2 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |