SCHEMBL5329478

SCHEMBL5329478

CC(Cc1ccc(OC(C)(C)C(=O)O)cc1)NC(=O)c1ccc(C(F)(F)F)cc1F

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.54
PPARD Q03181 18/20 0.54
PPARG P37231 16/20 0.54
CNR1 P21554 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5326681 0.92 CNR1 (0.48) PPARAPPARDPPARGCNR1
SCHEMBL14399395 0.89 PPARA (0.45) PPARAPPARDPPARGCNR1
SCHEMBL5321440 0.84 POLB (0.54) PPARAPPARGCNR1
SCHEMBL5351942 0.84 PPARA (0.47) PPARAPPARDPPARGCNR1
SCHEMBL5330018 0.84 PPARA (0.47) PPARAPPARDPPARGCNR1
SCHEMBL5324074 0.83 CDK2 (0.54) PPARAPPARDPPARG
SCHEMBL5324085 0.82 PPARA (0.48) PPARAPPARDPPARGCNR1
SCHEMBL5322668 0.82 CNR1 (0.46) PPARAPPARDPPARGCNR1
SCHEMBL14399420 0.82 PPARA (0.47) PPARAPPARDPPARGCNR1
SCHEMBL5325989 0.82 PPARA (0.47) PPARAPPARDPPARGCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007118963-A2 SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF GENFIT (FR) 2007-10-25 WO claimed
WO-2007118963-A2 SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF GENFIT (FR) 2007-10-25 WO disclosed