Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336636 | 0.99 | CLK1 (0.67) | CLK1SMN1; SMN2HTTRAB9APOLB | |
| SCHEMBL5329733 | 0.93 | CLK1 (0.68) | CLK1SMN1; SMN2HTTRAB9APOLB | |
| SCHEMBL5330710 | 0.89 | CLK1 (0.68) | CLK1SMN1; SMN2HTTRAB9APOLB | |
| SCHEMBL14520833 | 0.89 | CLK1 (0.68) | CLK1SMN1; SMN2HTTRAB9APOLB | |
| SCHEMBL5336629 | 0.88 | CLK1 (0.67) | CLK1SMN1; SMN2HTTRAB9APOLB | |
| SCHEMBL5331662 | 0.87 | SMN1; SMN2 (0.62) | CLK1SMN1; SMN2HTTRAB9APOLB | |
| SCHEMBL5334215 | 0.87 | SLC27A1 (0.58) | CLK1SMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL14520798 | 0.87 | CLK1 (0.65) | CLK1SMN1; SMN2HTTRAB9APOLB | |
| SCHEMBL14520797 | 0.86 | CLK1 (0.64) | CLK1SMN1; SMN2HTTRAB9APOLB | |
| SCHEMBL5461588 | 0.86 | HDAC1 (0.58) | CLK1POLBALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070088043-A1 | Novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED. (IN) | 2007-04-19 | — | — | US | claimed |
| WO-2007045962-A2 | NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | disclosed |
| US-20070088043-A1 | Novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED. (IN) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088043-A1 | Novel HDAC inhibitors | HDAC1, HDAC11, HDAC5 | CLK1 2197/4885SMN1; SMN2 3872/4885HTT 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.