Sugi Predict

Sugi Predict / Targets / SLC27A1

SLC27A1

Long-chain fatty acid transport protein 1 · Q6PCB7 · SLC27A1 on Sugi Atlas →

1,264 patent compounds predicted against SLC27A1, 713 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL20271113 SCHEMBL20271113 0.59 10/20
SCHEMBL20271781 SCHEMBL20271781 0.54 10/20
SCHEMBL20284452 SCHEMBL20284452 0.51 8/20
SCHEMBL8260087 SCHEMBL8260087 0.41 8/20
SCHEMBL6929102 SCHEMBL6929102 0.48 7/20
SCHEMBL11230145 SCHEMBL11230145 0.47 7/20
SCHEMBL4203551 SCHEMBL4203551 0.62 6/20
SCHEMBL20271988 SCHEMBL20271988 0.57 6/20
SCHEMBL9158791 SCHEMBL9158791 0.48 6/20
SCHEMBL3162896 SCHEMBL3162896 0.46 6/20
SCHEMBL15024313 SCHEMBL15024313 0.42 6/20
SCHEMBL4197541 SCHEMBL4197541 0.67 5/20
SCHEMBL4209247 SCHEMBL4209247 0.66 5/20
SCHEMBL4212070 SCHEMBL4212070 0.66 5/20
SCHEMBL18559230 SCHEMBL18559230 0.65 5/20
SCHEMBL4206813 SCHEMBL4206813 0.61 5/20
SCHEMBL14732156 SCHEMBL14732156 0.60 5/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL11266059) 0.60 5/20
SCHEMBL4208962 SCHEMBL4208962 0.58 5/20
SCHEMBL4217981 SCHEMBL4217981 0.58 5/20

Clinical trials — most relevant to SLC27A1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Hepato-renal Regulation of Water Conservation in Heart Failure Patients With SGLT-2 Inhibitor Treatment PHASE4COMPLETED
Atorvastatin, L-Carnitine and Non-Alcoholic Steatohepatitis PHASE2UNKNOWN
The Effects of Coenzyme A Combined With Abiraterone on Patients With CRPC PHASE1/PHASE2UNKNOWN
Metabolic Cofactor Supplementation in Obese Patients With Non-Alcoholic Fatty Liver Disease PHASE2COMPLETED
Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) Patients PHASE2COMPLETED
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
Bioavailability of Paracetamol, Amoxicillin and Talinolol Before, Immediately and One Year After Gastric Bypass Operation PHASE1COMPLETED
Carnitine Consumption and Augmentation in Pulmonary Arterial Hypertension PHASE1COMPLETED
Liver Positron Emission Tomography (PET) Study of Non Alcoholic Fatty Liver Disease EARLY_PHASE1COMPLETED
Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise nanCOMPLETED
Potential Association of a Common L-FABP Polymorphism With Lipid-induced Hepatic Insulin Resistance nanCOMPLETED
High Fat Diet for Cardiac Metabolic Reprogramming nanRECRUITING
Tissue Lipids and Insulin Resistance nanWITHDRAWN
for Adipose Tissue DIabetes VAriants (fATDIVA) nanCOMPLETED
Effect of a PPAR-Alpha Agonist on the Age Related Changes in Myocardial Metabolism and Mechanical Function nanUNKNOWN
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy nanCOMPLETED
Duality of Lipids: the Athlete's Paradox nanCOMPLETED
Oxalate and Citrate in Humans - Response to Citrate nanRECRUITING
Effects of Parenteral L-carnitine Supplementation in Premature Neonates nanCOMPLETED
Oligofructose-enriched Inulin for the Treatment of Mild to Moderate Active Ulcerative Colitis nanCOMPLETED
Lactate Profile and Fat Oxidation During Exercise nanCOMPLETED
The Role of Arachidonic Acid Metabolites, From Patients With Metabolic Syndrome nanUNKNOWN
Screening of Healthy Adults for Genetic Variations That Control Fatty Acid Processing nanCOMPLETED
MARS: Magnetic Resonance Study: A Novel Assessment of Placental Function nanCOMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity nanCOMPLETED
Lifestyle Intervention in Preparation for Pregnancy (LIPP) nanCOMPLETED
Intraumbilical Amino Acids and Glucose Supplementation Via Port by Severe IUGR in Human Fetuses nanCOMPLETED
Systemic Biomarkers of Brain Injury From Hyperammonemia nanRECRUITING
Familial Partial Lipodystrophy Study nanCOMPLETED
The RolE oF Androgen Excess in MUscle Energy MetaboLism in Women With PolyCystic Ovary Syndrome (REFUEL PCOS) Study 2 nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a SLC27A1 binder may also engage these)

ProteinNameSimilarity
Q60714 — 0.995 Q60714 →
Q3ZKN0 — 0.991 Q3ZKN0 →
P97849 — 0.991 P97849 →
Q4R3Y4 — 0.987 Q4R3Y4 →
Q6P1M0 — 0.986 Q6P1M0 →
Q5RDY4 — 0.980 Q5RDY4 →
Q91VE0 — 0.978 Q91VE0 →
P25409 — 0.952 P25409 →
P24298 — 0.952 P24298 →
ALG1 Chitobiosyldiphosphodolichol beta-mannosyltransferase 0.951 landscape →
Q5R7A2 — 0.950 Q5R7A2 →
A2AI05 — 0.949 A2AI05 →
Q8JZN7 — 0.949 Q8JZN7 →
RHOT2 Mitochondrial Rho GTPase 2 0.948 landscape →
Q8QZR5 — 0.948 Q8QZR5 →
Q7TSA0 — 0.948 Q7TSA0 →
AGPAT2 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 0.948 landscape →
Q4V9J0 — 0.947 Q4V9J0 →
A4IFH5 — 0.947 A4IFH5 →
LPCAT1 Lysophosphatidylcholine acyltransferase 1 0.947 landscape →
Q5E9M9 — 0.946 Q5E9M9 →
Q9D0L4 — 0.946 Q9D0L4 →
NOX5 NADPH oxidase 5 0.946 landscape →
ACSL1 Long-chain-fatty-acid--CoA ligase 1 0.945 landscape →
E1BNQ4 — 0.945 E1BNQ4 →
O97583 — 0.945 O97583 →
PNKP Bifunctional polynucleotide phosphatase/kinase 0.945 landscape →
Q27979 — 0.945 Q27979 →
Q1HAQ0 — 0.944 Q1HAQ0 →
P84850 — 0.944 P84850 →