Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329766 | 0.90 | GAA (0.64) | TSHRGAAMEN1KMT2AHPGD | |
| SCHEMBL5422195 | 0.89 | GAA (0.62) | TSHRGAAMEN1KMT2AHPGD | |
| SCHEMBL5330985 | 0.87 | TSHR (0.56) | TSHRGAAMEN1KMT2AHPGD | |
| SCHEMBL5336800 | 0.82 | KMT2A (0.80) | TSHRGAAMEN1KMT2AHPGD | |
| SCHEMBL5329256 | 0.82 | ALDH1A1 (0.58) | TSHRGAAMEN1KMT2AHPGD | |
| SCHEMBL5332292 | 0.82 | GAA (0.58) | TSHRGAAMEN1KMT2AHPGD | |
| SCHEMBL5331047 | 0.80 | KMT2A (0.62) | TSHRGAAMEN1KMT2AHPGD | |
| SCHEMBL5330488 | 0.80 | KMT2A (0.62) | TSHRGAAMEN1KMT2AHPGD | |
| SCHEMBL5416217 | 0.79 | ALDH1A1 (0.60) | TSHRGAAMEN1KMT2AHPGD | |
| SCHEMBL5330577 | 0.78 | TDP1 (0.59) | TSHRGAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |