Alcohol

Alcohol

SCHEMBL5331218

CCO.Cc1ccc(CCO)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.54
CYP1A2 P05177 1/20 0.52
CYP2A6 P11509 1/20 0.52
TAAR1 Q96RJ0 1/20 0.52
CYP4F2 P78329 4/20 0.52
CYP4A11 Q02928 4/20 0.52
TDP1 Q9NUW8 2/20 0.50
IGF1R P08069 1/20 0.45
ALOX15 P16050 1/20 0.45
IDO1 P14902 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20413 0.95 CA2 (0.59) CA2CYP1A2CYP2A6TAAR1CYP4F2
SCHEMBL15725304 0.88 CA2 (0.52) CA2CYP1A2CYP2A6TAAR1CYP4F2
Formaldehyde SCHEMBL17697788 0.88 CA2 (0.52) CA2CYP1A2CYP2A6TAAR1CYP4F2
SCHEMBL15853471 0.87 CA2 (0.46) CA2CYP1A2CYP2A6TAAR1CYP4F2
SCHEMBL9009517 0.87 CA2 (0.46) CA2CYP1A2CYP2A6TAAR1CYP4F2
Toluene SCHEMBL1120065 0.86 TDP1 (0.65) CA2CYP1A2CYP2A6TAAR1CYP4F2
Toluene SCHEMBL1290122 0.86 TDP1 (0.65) CA2CYP1A2CYP2A6TAAR1CYP4F2
Toluene SCHEMBL2589614 0.86 TDP1 (0.65) CA2CYP1A2CYP2A6TAAR1CYP4F2
Toluene SCHEMBL9412512 0.86 TDP1 (0.65) CA2CYP1A2CYP2A6TAAR1CYP4F2
Toluene SCHEMBL9501175 0.86 TDP1 (0.65) CA2CYP1A2CYP2A6TAAR1CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1773853-A1 MONOPHOSPHINE COMPOUNDS, TRANSITION METAL COMPLEXES THEREOF AND PRODUCTION OF OPTICALLY ACTIVE COMPOUNDS USING THE COMPLEXES AS ASYMMETRIC CATALYSTS Sumitomo Chemical Company, Limited (JP) 2007-04-18 EP disclosed
WO-2005121157-A1 MONOPHOSPHINE COMPOUNDS, TRANSITION METAL COMPLEXES THEREOF AND PRODUCTION OF OPTICALLY ACTIVE COMPOUNDS USING THE COMPLEXES AS ASYMMETRIC CATALYSTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-12-22 WO disclosed