Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330103 | 0.94 | HTR6 (0.52) | HTR6CYP3A4CYP2D6HTR1ADRD2 | |
| SCHEMBL5334193 | 0.91 | HTR6 (0.47) | HTR6CYP3A4CYP2D6HTR1ADRD2 | |
| SCHEMBL5414230 | 0.88 | HTR6 (0.58) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL5333236 | 0.88 | HTR6 (0.54) | HTR6CYP3A4CYP2D6KLK7 | |
| SCHEMBL5330301 | 0.86 | HTR6 (0.60) | HTR6CYP3A4CYP2D6HTR1ADRD2 | |
| SCHEMBL5330256 | 0.85 | HTR6 (0.53) | HTR6CYP3A4CYP2D6HTR1ADRD2 | |
| SCHEMBL5325858 | 0.84 | HTR6 (0.60) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL5327724 | 0.84 | HTR6 (0.53) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5334698 | 0.84 | HTR6 (0.58) | HTR6CYP3A4CYP2D6HTR1ADRD2 | |
| SCHEMBL5330681 | 0.83 | HTR6 (0.49) | HTR6HTR1ADRD2HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |