Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 4/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.37 |
| ▸ | SMC2 | O95347 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.37 |
| ▸ | SMC1A | Q14683 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.37 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968996 | 0.91 | MEN1 (0.45) | CSF1RMAP2K1SMC2EGFRCSNK2A2 | |
| SCHEMBL3973358 | 0.86 | MAP2K1 (0.53) | POLBMAP2K1SMC2EGFRCSNK2A2 | |
| SCHEMBL15088158 | 0.85 | MEN1 (0.44) | CSF1RMAP2K1SMC2EGFRCSNK2A2 | |
| SCHEMBL3978143 | 0.81 | MAP2K1 (0.41) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL3974144 | 0.81 | MAP2K1 (0.40) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL13842002 | 0.80 | MAP2K1 (0.50) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL5406502 | 0.79 | MAP2K1 (0.49) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL3974790 | 0.77 | MAP2K1 (0.34) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL3974792 | 0.77 | MAP2K1 (0.34) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL3978828 | 0.77 | CSF1R (0.43) | CSF1RMAP2K1SMC2EGFRCSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007022529-A2 | METHOD OF TREATING INFLAMMATORY DISEASES | ARRAY BIOPHARMA INC. (US) | 2007-02-22 | — | — | WO | disclosed |