Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.65 |
| ▸ | PPARG | P37231 | 15/20 | 0.65 |
| ▸ | PPARD | Q03181 | 7/20 | 0.65 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.63 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380084 | 0.88 | PPARA (0.75) | PPARAPPARGPPARD | |
| SCHEMBL5380087 | 0.88 | PPARA (0.75) | PPARAPPARGPPARD | |
| SCHEMBL4993002 | 0.87 | PPARA (0.69) | PPARAPPARGPPARDSRR | |
| SCHEMBL1670312 | 0.87 | PPARA (0.69) | PPARAPPARGPPARDSRR | |
| SCHEMBL6422692 | 0.83 | PPARA (0.65) | PPARAPPARGPPARD | |
| SCHEMBL543815 | 0.81 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL3233074 | 0.81 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL17680422 | 0.81 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL5543269 | 0.81 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL5399556 | 0.81 | PPARG (0.55) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737809-A4 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE IN TREATING METABOLIC DISORDERS | AMGEN INC (US) | 2007-10-17 | — | — | EP | disclosed |
| EP-1737809-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE IN TREATING METABOLIC DISORDERS | Amgen, Inc (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005086661-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE IN TREATING METABOLIC DISORDERS | AMGEN INC. (US) | 2005-09-22 | — | — | WO | disclosed |