Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 5/20 | 0.42 |
| ▸ | BRD2 | P25440 | 3/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TAF1 | P21675 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | BRWD1 | Q9NSI6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222904 | 0.90 | NPSR1 (0.46) | NPSR1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL223583 | 0.87 | BRD4 (0.55) | SMN1; SMN2BRD4BRD2BRD3CYP3A4 | |
| SCHEMBL225509 | 0.87 | BRD4 (0.55) | SMN1; SMN2BRD4BRD2BRD3CYP3A4 | |
| SCHEMBL225291 | 0.85 | MAPT (0.42) | NPSR1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL222992 | 0.80 | LMNA (0.59) | NPSR1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL532665 | 0.79 | MAPT (0.48) | NPSR1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL225382 | 0.78 | BRD4 (0.45) | NPSR1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL220928 | 0.78 | BRD4 (0.58) | SMN1; SMN2BRD4BRD2BRD3CYP3A4 | |
| SCHEMBL222269 | 0.78 | BRD4 (0.58) | SMN1; SMN2BRD4BRD2BRD3CYP3A4 | |
| SCHEMBL15890804 | 0.76 | BRD4 (0.45) | NPSR1MAPTLMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415764-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT | Kowa Company, Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |