Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14346787 | 1.00 | HTR6 (0.68) | HTR6 | |
| SCHEMBL10263415 | 0.88 | HTR6 (0.66) | HTR6 | |
| SCHEMBL21869968 | 0.88 | HTR6 (0.66) | HTR6 | |
| SCHEMBL5331614 | 0.84 | HTR6 (0.68) | HTR6 | |
| SCHEMBL315347 | 0.81 | HTR6 (1.00) | HTR6 | |
| SCHEMBL315247 | 0.81 | HTR6 (1.00) | HTR6 | |
| SCHEMBL316484 | 0.81 | HTR6 (0.81) | HTR6 | |
| SCHEMBL12428612 | 0.81 | HTR6 (0.81) | HTR6 | |
| Hydrochloric Acid SCHEMBL316371 | 0.80 | HTR6 (0.98) | HTR6 | |
| SCHEMBL2856362 | 0.80 | HTR6 (0.69) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831159-A1 | TETRALIN AND INDANE DERIVATIVES AND USES THEREOF | F. Hoffmann-Roche AG (CH) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006066790-A1 | TETRALIN AND INDANE DERIVATIVES AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2006-06-29 | — | — | WO | disclosed |