Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.83 |
| ▸ | TP53 | P04637 | 4/20 | 0.83 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.69 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329155 | 0.90 | MAPT (0.80) | MAPTTP53PAX8CREBBPKDM4E | |
| SCHEMBL11229376 | 0.88 | MAPT (0.69) | MAPTTP53KDM4EALDH1A1LMNA | |
| SCHEMBL5325640 | 0.88 | PAX8 (0.85) | MAPTTP53PAX8CREBBPKDM4E | |
| Hydrochloric Acid SCHEMBL11233895 | 0.85 | MEN1 (0.65) | MAPTTP53KDM4EALDH1A1PKM | |
| SCHEMBL5332873 | 0.83 | PAX8 (0.85) | MAPTTP53PAX8CREBBPKDM4E | |
| SCHEMBL5929643 | 0.83 | MAPT (0.65) | MAPTTP53SMN1; SMN2GAA | |
| SCHEMBL5329104 | 0.83 | CREBBP (0.82) | MAPTTP53PAX8CREBBPKDM4E | |
| SCHEMBL5322774 | 0.83 | CREBBP (0.82) | MAPTTP53PAX8CREBBPKDM4E | |
| SCHEMBL5332891 | 0.82 | PAX8 (0.83) | MAPTTP53PAX8CREBBPKDM4E | |
| SCHEMBL5328005 | 0.82 | PAX8 (0.83) | MAPTTP53PAX8CREBBPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007139496-A1 | QUINOLINE DERIVATIVES ACTING AS TYROSINE KINASE INHIBITORS | CLANOTECH AB (SE) | 2007-12-06 | — | — | WO | disclosed |