SCHEMBL5331916

SCHEMBL5331916

CCOC(=O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1C(=O)OCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
HPGD P15428 4/20 0.52
MAPT P10636 4/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
GAA P10253 3/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
NR1H2 P55055 1/20 0.50
NR1H3 Q13133 1/20 0.50
PDE4D Q08499 1/20 0.48
FHIT P49789 1/20 0.47
KMT2A Q03164 3/20 0.46
POLB P06746 1/20 0.46
CYP3A4 P08684 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
NPC1 O15118 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7203276 0.93 ALDH1A1 (0.50) ALDH1A1HPGDMAPTSMN1; SMN2GAA
SCHEMBL522852 0.93 ALDH1A1 (0.54) ALDH1A1HPGDMAPTSMN1; SMN2GAA
SCHEMBL7074076 0.92 ALDH1A1 (0.47) ALDH1A1HPGDMAPTSMN1; SMN2GAA
SCHEMBL5336522 0.92 ALDH1A1 (0.47) ALDH1A1HPGDMAPTSMN1; SMN2GAA
SCHEMBL6928988 0.85 ALDH1A1 (0.49) ALDH1A1HPGDMAPTSMN1; SMN2GAA
SCHEMBL2191141 0.85 ALDH1A1 (0.49) ALDH1A1HPGDMAPTSMN1; SMN2GAA
SCHEMBL5336896 0.82 ALDH1A1 (0.48) ALDH1A1MAPTSMN1; SMN2GAANR1H2
SCHEMBL11008658 0.82 ALDH1A1 (0.62) ALDH1A1HPGDMAPTSMN1; SMN2GAA
SCHEMBL10414166 0.81 ALDH1A1 (0.46) ALDH1A1HPGDMAPTSMN1; SMN2GAA
SCHEMBL6208446 0.80 ALDH1A1 (0.45) ALDH1A1HPGDMAPTSMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7307041-B2 Stabilizers for use in substantially light-insensitive thermographic recording materials AGFA HEALTHCARE (BE) 2007-12-11 US disclosed
EP-1637338-B1 Substantially light-insensitive thermographic recording material AGFA GEVAERT (BE) 2007-04-04 EP disclosed
US-20060063670-A1 Stabilizers for use in substantially light-insensitive thermographic recording materials AGFA-GEVAERT (BE) 2006-03-23 US disclosed
EP-1637338-A1 Substantially light-insensitive thermographic recording material Agfa-Gevaert (BE) 2006-03-22 EP disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed