Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5477723 | 0.91 | HTR6 (0.52) | HTR6 | |
| SCHEMBL5431957 | 0.86 | HTR6 (0.54) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL5327825 | 0.80 | HTR6 (0.52) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL5331965 | 0.80 | HTR6 (0.67) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL3587283 | 0.78 | HTR6 (0.72) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL5330870 | 0.76 | HTR6 (0.52) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL3559034 | 0.76 | HTR6 (0.55) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL5332274 | 0.75 | HTR6 (0.55) | HTR6 | |
| SCHEMBL3601701 | 0.72 | HTR6 (0.68) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL5467982 | 0.72 | HTR6 (0.53) | HTR6HTR1ADRD2HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | claimed |
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |